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Less immune-cell infiltration into the postischemic area suggested either that Fer-1 directly inhibits leukocyte transmigration or that the local proinflammatory microenvironment was less chemoattractive, presumably by less damage-associated molecular pattern (DAMP) release due to less ferroptotic cell death

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Animal studies show the peptide can recruit the azygos vein system during caval vein occlusion, parasagittal veins for compromised brain circulation, and pancreaticoduodenal arteries when mesenteric vessels become blocked