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B., West, M

doi: 10.1016/j.celrep.2023.112977 38 MongelliVSalehMC

In men, hyperprolactinemia causes loss of libido, erectile dysfunction, and infertility

Experimental research in rat aortic endothelial cells showed that capsaicin-induced TRPV1 activation elevates NO levels by up to 29%, alongside increased levels of the essential cofactor BH4 and cGMP, which are critical for eNOS function and downstream signaling, respectively