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In contrast, in the hippocampus the decrease in BDNF mRNA expression in rats treated with BSO + GBR 12909 was reversed after administration of MIR and also by co-treatment with ineffective doses of aripiprazole and MIR

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Mental illness ranks among the leading causes of disability worldwide, accounting for 18.9% of years lived with disability [21], with an estimated $8.5 trillion in lost economic output attributed to mental, neurological, and substance use disorders [22]