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doi: 10.1007/s10571-017-0469-1 Summary Keywords sinomenine, cerebral ischemia, drug delivery, neuroinflammation, bonebrainaxis Citation Li X, Zhang X, Wang T, Li H, Li Y, Liu J and Bai Y (2025) Sinomenine in cerebral ischemia: mechanisms, delivery strategies, and the emerging multifunctional biomaterials of the bonebrain axis