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In addition, ferroptosis is orchestrated by a variety of cellular metabolic pathways, including redox homeostasis, iron metabolism, mitochondrial activity, amino acid and lipid and sugar metabolism, and various signaling pathways [7, 10]

Cysteine serves as a precursor for glutathione, a central intracellular antioxidant, while its dysregulation is intricately linked to cardiovascular disease, diabetes, neurodegenerative conditions, and cancer

In the cortex of cuprizone treated animals and controls, staining intensity and continuity of the tight junction proteins occludin and ZO1 was similar (Fig

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