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2018;13:e0192801

Acknowledgments All graphical illustrations in this work were prepared using BioRender ( Conflict of interest The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

The OsDHAR sequence was then manually built into the electron density map using the COOT program and restrained refinement was performed using the REFMAC5 program 32,33

Research Use Disclaimer The compounds distributed by USA PEPTIDE SCIENCES , including GHK-Cu 1g raw topical-grade powder, are designated strictly for laboratory research purposes only