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Transcriptomic studies of cells exposed to GHK-Cu have reported broad gene-expression changes affecting hundreds to thousands of genes in some studies

doi: 10.1016/j.schres.2019.10.054, 61

The GCLC floxed mice (Cre-negative) shows lowered levels of glutathione in blood probably because introduced loxp sequences interrupt GCLC expression (Fig

(2022) showed that AP (150500 mg/kg) decreased tracheal contractile responses to carbachol and increased NO bioavailability, reinforcing its bronchodilatory potential