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DIU analysis revealed 1119 genes exhibiting DIU during the experimental set-up of this article

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lutein and zeaxanthin absorb blue visible light (400500 nm)

TARDBP -family fibroblasts display an elevated oxidative stress burden respect to unrelated control fibroblasts Increased oxidative stress is one of the main pathological features of ALS, including TARDBP fALS cases, and a possible driver of disease progression [26]

Notably, Withaferin A treatment also increased the levels of mono-oxygenated (+1) PE and PC species, which may be products of lipids peroxidized via the lipid peroxidase activity of GPX4 16