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AD patients are also more susceptible to SARS-CoV-2 infection, with AD being a risk factor for a poor prognosis of COVID-19 infection [120]

Because TG2 activity is highly associated with cellular redox status and alterations in the bidirectional flux of cellular thiol modulate TG2 activity, regulation of thiol flux in cells probably affects the TG2-mediated aggregation of the GST tag and its interaction with cellular proteins