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Lancet 355 , 15181519 (2000)

Skin Brightening Promotes a clearer, more even complexion by reducing hyperpigmentation

Vice versa, confronted with the permanent central venous occlusion, the therapy effect is starting centrally, from the occluded superior sagittal sinus, as a prime noxious event (note, instead increased positive pressure, BPC 157-rats presented the negative pressure values close to those noted in the superior sagittal sinus of the healthy rats)