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2023, Dec, 22;14 Szgi T, Borsos BN, Masic D, Radics B, Bella Z, Bnfi A, et al

After accounting for other factors, testosterone use was linked to a 34% lower death rate over the study period

This paper demonstrates the advantages of direct reprogramming of ALS patient fibroblasts, via induced neural progenitor cells, into astrocytes, which are toxic to motor neurons in coculture and are non-clonal and retain the epigenetic features of ageing

Organoids were harvested at day 7 (Matrigel) or day 4 (collagen), with both conditions collected at passage 2, each representing comparable growth stages for scRNA-seq analysis