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A number of these key mechanistic events are also reproduced in humans, suggesting that cellular responses to APAP overdose are conserved between mice and men

Scheres SHW, Ryskeldi-Falcon B, Goedert M

Someone has to be the first one to undergo surgery," he said, "There's always someone who has to do this this is kind of like the first part of medicine

Chemical and genetic screens can be performed to identify DTP mechanisms, which can be functionally interrogated with perturbation experiments 64,156,256