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The implication is that IGF-1 LR3 might exhibit increased efficacy in studies focused on cellular proliferation compared to its unmodified counterpart, IGF-1

Double induction (DI) chemotherapy for patients (pts) with newly diagnosed acute myelogenous leukemia (AML) or myelodysplastic syndromes (MDS)

Supplementary information Supplementary Tables 18 and Figs

In the oxidative half of the mechanism, Cys63 nucleophilically attacks the nearest sulfide unit in the glutathione disulfide (GSSG) molecule, which creates a mixed disulfide bond (GS-Cys58) and a GS- anion