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Single colony isolates were used to validate the scanning allelic diversity pipelines

Rather than viewing copper simply as a free metal ion, coordination chemistry explains how binding to a peptide creates a new chemical complex with distinct structural and physicochemical properties

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In hereditary cancers, heterozygous mutations are usually accompanied by trisomy of the whole chromosome 7, suggesting that when only a single allele is mutated the mutation must be present in multiple copies to produce the full transformed phenotype [Schmidt et al