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Lipidomic analyses showed that depletion of either FADS1 or FADS2 through siRNA transfection successfully reduced AA levels, although only FADS2 depletion suppressed ferroptosis

CLr of unchanged drug is significant

doi: 10.1097/DAD.0b013e3181cb3fdd 129

A relative decline in the efficiency of this potential compensatory mechanism, resulting in a less robust Gln-Glu cycle, may contribute to the manifestation of sensory sensitivity-related symptoms