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Author contributions: Writing-review & editing: TZ, YY, XQ, XX, YT, and QQ

Notably, the gene FLG showed a significant difference in mutation frequency between the MVI-positive and MVI-negative groups (p=0.017)

In LSS, the expression of the E3 ubiquitin ligase Smurf1 is markedly elevated, which promotes fibrosis and oxidative stress in LF cells, contributing to the progression of LSS by facilitating the ubiquitination and degradation of NRF2 [112]

118-120 Vestibular evoked myogenic potentials are electrical signals that can be measured in the neck or eye muscles and may provide valuable diagnostic information about the function of the vestibular system