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Extracellular vesicles: novel mediators of cell communication in metabolic disease

Though the benefits of these synthetic therapeutic immunomodulatory agents cannot be disputed, their use is frequently associated with adverse side effects

doi: 10.3390/biology11020196 124 ZwetslootKJohnCLawrenceMBattistaRShanelyRA

Importantly, much of HDLs (and apoA-Is) inhibition of macrophage activation is mediated through altering cholesterol levels in plasma membrane lipid rafts through cholesterol efflux mediated by ABCG1/SR-BI and ABCA1