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Liou GY, Storz P

Pedrera et al (135) validated the factors causing membrane rupture due to ferroptosis in cell models such as NIH-3T3, HT-1080, Mda-157 and H441 cells

3.4 Pg promotes upregulation of FMO3 expression in the liver of mice and fatty degeneration of the liver TMA originating from the gut, enters to the liver via the bloodstream and undergoes oxidation to TMAO, a process catalyzed by the FMO family, particularly FMO3, in the liver (Shih et al., 2015)