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TLC-2716 and TLC-6665 demonstrated comparable binding to and repression of LXR and LXR activity with half-maximal effective concentrations (EC 50 ) of 715 and 1417 nM, respectively (Fig

Once these missing links have been uncovered, it is highly likely that precision medicine tailored for not only the different IBS subtypes but also for individual genetic and dietary differences can be engineered

Despite recent developments in the field of metal-based catalytic drugs, these compounds are generally associated with a poor spatial and temporal control of the treatment as well as poor cancer selectivity, resulting in potential side effects and non-ideal drug doses 29

Bacteriocins, antimicrobial peptides from bacterial origin: overview of their biology and their impact against multidrug-resistant bacteria