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Figure 2 For further analysis, stages 1 and 2 of CKD were grouped together as early stage CKD, while stages 3 and 4 were grouped together as late stage CKD

The distinctive blue color of reconstituted GHK-Cu solutions indicates intact copper-peptide coordination, serving as a visual quality indicator that the compound remains active

Free intracellular PUFAs form esterification products through the binding of coenzyme A (CoA) and acyl-coenzyme A synthase long-chain family member 4 (ACSL4), which are subsequently transported to phospholipid-like lipids (PL) of the cell membrane via lysophosphatidylcholine acyltransferase 3 (LPCAT3) (26, 27)

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