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Anti-inflammatory and hepatoprotective agents, such as magnesium isoglycyrrhizinate and polyene phosphatidylcholine, should be administered

More injections and/or higher doses will be needed for better results

Interestingly, in another study from Song, betaine could restore abnormal adipokine levels in NAFLD, and it upregulated adiponectin and downregulated leptin and resistin in adipose cells to attenuate the dysregulated lipid metabolism

Furthermore, besides such evidence demonstrating a regulatory role of the molecular clock on NF-B signaling pathway, it has been also observed that, vice versa, the activation of NF-B directly impacts on the transcriptional activity of the core clock components