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Cycloxygenase-2 (Cox-2) catalyzes the metabolic switch of arachidonic acid to prostaglandins, which inspires Cox-2s pro-inflammatory and tumor-promoting actions

After removing makeup and cleansing your face thoroughly (consider a double-cleanse if you wear heavy SPF/makeup, e.g

Cytoskeleton 64 , 794807 (2007)

This cellular demise can subsequently diminish ECM synthesis, which in turn, exacerbates the degradative changes within the IVD microenvironment, perpetuating a cycle that further compromises the viability of NPCs