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Once inside, this activated Smad complex binds to specific Smad binding elements within the genome to execute its regulatory function, such as modulating fibrin expression (156, 157)

Supplementary material The Supplementary Material for this article can be found online at: References 1 MongaIKaurKDhandaSK

Among various cell surface receptors, IGF-1R (insulin-like growth factor receptor) expression is important for myoblast proliferation and maintenance of normal muscle mass 21,22,23,24,25,26