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The homozygous deletion of the GSTT1 locus (null genotype) and the GSTM1 -null genotype can result in a deficiency of the detoxification capacity of these isoenzymes and an increase in the susceptibility to carcinogenic compounds

Springer, Berlin, pp 2143 Fincheira P, Quiroz A, Tortella G et al (2021) Current advances in plant-microbe communication via volatile organic compounds as an innovative strategy to improve plant growth

This aligns with our earlier observation that CQ treatment selectively rescued unphosphorylated Vangl1 in siScramble-treated cells