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Consulting with a Healthcare Professional Why it Matters: Before embarking on any supplementation, consulting with a healthcare professional is paramount

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Additional symptoms and comorbidities, such as pain (e.g., migraines, neuropathy) and mast cell activation syndrome (MCAS), are also prevalent in both conditions

70 The European Medicines Agencys Pharmacovigilance Risk Assessment committee recommended risk minimization measures (RMM) for flupirtine (use only after other analgesics were trialled, patients restricted to up to two week-long treatments, with weekly LFT) due to concern of rare serious liver injury associated with long-term use of flupirtine