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Testosterone Replacement Therapy (TRT) Mechanism TRT restores testosterone to healthy levels (target: 600-900 ng/dL) in men whose bodies no longer produce enough

However, there are also risks and side effects associated with this surgery

Peptide drugs have been FDA-approved for decades, across dozens of therapeutic categories, from diabetes management to HIV-associated lipodystrophy to rare mitochondrial disorders

By the same time, the FDA approved the use of a equimolar combination of IGF-1 and IGFBP-3 (Mecasermin Rinfabate, iPlex), suggesting that it would be a better choice, seeming as it will require lower doses because of the augmented half-life of the molecule and buffering effect on concentration