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doi: 10.1016/j.intimp.2021.108175 233 Dvir-GinzbergMMobasheriAKumarA

FIGURE 3 Genetic Substrate MVP is known to be associated with several connective tissue disorders such as Marfan syndrome and Loeys-Dietz syndrome, which are beyond the scope of this review ( Similar to syndromic forms of MVP, familial inheritance by autosomal dominant ( DCHS1 (dachsous cadherin-related 1) ( TNS1 (tensin 1) ( LMCD1 (LIM and cysteine rich domains 1) ( DZIP1 (DAZ interacting zinc finger protein 1) ( GLIS1 (GLIS family zinc finger 1) ( FLNA (filamin A) ( The recent association of MVP with pathogenic variants in several known cardiomyopathy genes, such as TTN (titin) and FLNC (filamin C) could explain disproportionate LV remodeling ( n = 96, 97%), in order to evaluate the genetic yield of the known causative MVP genes and detect possible new genetic variants

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10.3390/cancers12061370 11 CavalettiG.TrediciG.BragaM.TazzariS