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Description

Upon exposure to excessive Cu, cells activate the assembly of necroptosomes by allowing MLKL pore entry and upregulating MLKL levels

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Due to the high levels of ROS, cancer cells have expressed high levels of ROS-scavenging enzymes which maintain resistance to ROS-driven cell death

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The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation

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