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Iron chelators are ferroptosis inhibitors that target free iron in labile iron pools and prevent iron from supplying electrons to oxygen to form ROS

Patients with PBC-NAFLD were more likely to have a higher percentage of treatment response compared to the PBC group, with a trend towards higher response rates at a five-year follow-up

Serotonin containing neurons have their cell bodies in the midline raphe nuclei of the brain stem and project to portions of the hypothalamus, the limbic system, the neocortex, and the spinal cord

This benefit is particularly important for individuals with compromised immune systems, such as the elderly, those with chronic illnesses, or individuals recovering from surgery or injury