These vitamins work together in our bodys metabolic pathways
Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms
If you think you dont need to take vitamin B12 supplements, you might need to think again
Vitamin B12 (cobalamin) is a water-soluble vitamin required for DNA synthesis, red blood cell formation, myelin maintenance, and methylation the biochemical process that regulates gene expression, neurotransmitter production, and homocysteine metabolism