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Description

A pivotal RCT in 116 cannabis-dependent adolescents found that NAC (1,200 mg twice daily) more than doubled the odds of a negative urine cannabinoid test compared to placebo (OR 2.4, 95% CI 1.1-5.2) (Gray et al., Am J Psychiatry, 2012) [76]

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10.1038/ng1001-160 380 YangM.LiangC.SwaminathanK.HerrlingerS.LaiF.ShiekhattarR.et al

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Notably, a peak in cell viability was observed at 25 mol/l of DAPA, followed by a decline with further increases in concentration (Fig

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