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[DOI] [PubMed] [Google Scholar] 12.Juraschek L.M., Kappenberg A., Amelung W

When using hydrocodone bitartrate and acetaminophen tablets with CYP3A4 inducers or discontinuing CYP3A4 inhibitors, follow patients at frequent intervals and consider increasing the opioid dosage if needed to maintain adequate analgesia or if symptoms of opioid withdrawal occur (see PRECAUTIONS, Drug Interactions)

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Therefore, the decay kinetics of GSNO based on absorption spectroscopy should agree with the NO generation kinetics