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Given our hypothesis that L1 GUS enzymes efficiently process drug glucuronides, we determined using ultra performance liquid chromatography (UPLC) the cleavage rates of the novel L1 GUS enzymes Fp GUS, Lr GUS, Rg GUS, as well as the ten additional enzymes in our GUS panel, with the physiologically relevant glucuronide metabolite of the NSAID diclofenac, DCF-G (Table 3 and Fig

153 Importantly, dual luciferase reporter gene experiments reveal that CEBPG, as a transcription factor, regulates ferroptosis of ovarian cancer cells primarily through transcriptional control of SLC7A11, affecting the metastasis of ovarian cancer cells