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Furthermore, HRMS-based non-targeted analyses using MS/MS structural elucidation allowed to identify other relatively minor metabolites related to APAP-Cys such as S-(5-acetylamino-2-hydroxyphenyl)mercaptopyruvic acid (SAMP), an APAP metabolite potentially formed by the transamination reaction of APAP-cysteine (see Fig.1), previously observed in mouse ( 29 )

The liver transforms free fatty acids into usable energy

Testing proteins, peptides, and PTMs for sex differences in abundance To reduce the potential for false positive sex differences, we filtered out proteins, peptides, and PTMs with fewer than 100 non-missing observations

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