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Assembling of the generated sequences to make contigs was performed using DNA Baser version 3x and the sequences aligned in MUSCLE version 3.8

Animal and cellular experiments have shown that curcumin can bind to TLRs and participate in regulating downstream inflammatory signaling pathways such as MAPK, NF-B, and AP-1, significantly reducing levels of inflammatory mediators such as IL-1, IL-6, TNF-, NO, and iNOS, thus achieving anti-inflammatory effects [29,65]

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