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Gammaproteobacteria , which synthesize an elongated version of the bacterial enzyme cytidine deaminase (CDD L ), may transform the chemotherapeutic agent gemcitabine (2,2-difluorodeoxycytidine) into its inactive derivative, 2,2-difluorodeoxyuridine (Kostic et al., 2012)

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doi: 10.1186/s12986-015-0056-8

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