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Vitamin B12 and folic acid deficiencies cause high homocysteine levels, which have been associated with increased atherosclerosis, stroke, arterial clots, and venous thrombosis risk

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Thus, the regulation of somatotrophs evolved to be less complex during vertebrate evolution [reviewed by Gahete et al

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M.RosenfeldtM.SchmitzW.JiangM.et al

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