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1 XPO-1 inhibitor therapy The upregulation of XPO1 inactivates tumor suppressor anti-neoplastic function, facilitating the transport of tumor suppressor proteins from the nucleus to the cytoplasm

Growth-hormone treatment and risk of diabetes Lancet 2000 355 : 19131914

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[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses