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10.1016/j.canlet.2015.11.044 238 MaJ.LiL.YueK.LiY.LiuH.WangP

Plasma protein extraction and digestion For the discovery cohort (2011), two separate preparations were made with either 1 or 2 L of plasma added to new tubes containing 2423 L of SDC buffer consisting of sodium deoxycholate 1% (DOC), tris(2-carboxyethyl) phosphine 10 mM (TCEP), chloroacetamide 40 mM and Tris 100 mM pH 8.5

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(2005) p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase