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To bridge this gap, the field needs to pursue advanced lipidomic profiling using patient biofluids (such as cerebrospinal fluid and plasma) to identify and quantify the specific oxidized PUFA species (e.g., oxPEs) that represent the ultimate executioners of the ferroptotic cascade [55,104]

Hemisphere that underwent FUS alone (i.e., FUS group) neither showed statistically sufficient plaque differences when comparing to cortex nor hippocampus

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And in our "EPIC study's bluster about pimobendan unravels as critical analysis finally takes hold" , we noted that several cardiologists were rejecting the EPIC authors' recommendation to start pimobendan at the first sign of heart enlargement, and calling for a "more measured approach"