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Data Animal Data In pregnant rats given twice weekly subcutaneous doses of 0.02, 0.1, and 0.5 mg/kg tirzepatide [0.03-, 0.07-, and 0.5-fold the maximum recommended human dose (MRHD) of 15 mg once weekly based on AUC] during organogenesis, increased incidences of external, visceral, and skeletal malformations, increased incidences of visceral and skeletal developmental variations, and decreased fetal weights coincided with pharmacologically-mediated reductions in maternal body weights and food consumption at 0.5 mg/kg

SU-PER B-12 Powder Horse Supplement Features & Benefits Supports energy, stamina and delayed fatigue Vitamin B-12 + Folic Acid for healthy red blood cell production Helps support oxygen delivery to working muscles Corn- and Soy-free, Apple-flavored formula Stabilized flaxseed meal supports healthy skin and coat Omega-3, -6 and -9 Fatty Acids Provides vitamin B-12 and folic acid, also known as vitamin B-9, to support healthy red blood cell production, energy and stamina

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doi: 10.1007/s12031-022-02053-3 209