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10.1016/j.tibs.2006.11.006 14 BrachsS.PolackJ.BrachsM.Jahn-HofmannK.ElvertR.PfenningerA.et al (2019)

We mention it here because we believe patients deserve to know what is being evaluated at their clinic, and what the honest state of the evidence is, rather than hearing about it first from an online forum or supplement retailer

The compound shows high enzymatic selectivity, preserves lean mass, and engages longevity-related pathways (e.g., SIRT1), but remains a nonFDA-approved research substance that is WADA-banned and should be used under medical guidance