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For example, platinum-based drugs are especially used for testicular cancer, which directly form DNA adducts and lead to intrastrand and interstrand cross-links [86]

Signaling pathways can also promote microtubule stabilization by inhibiting the activity of proteins that destabilize microtubules

On the one hand, tumor cells are metabolically dependent on methionine, and abnormal activation of its metabolic cycle is one of the hallmarks of HCC [91]