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Drosophila S2R+ cells were obtained from the Drosophila Genomic Research Centre (DGRC) and maintained at 25C

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Tumor suppression in humans relies on the immune system, but metastatic tumor cells can evade immune detection by using checkpoints like CTLA-4 and PD-1/PD-L1, thereby inhibiting immune responses and weakening anticancer immunity.This version simplifies and streamlines the information for better readability and clarity (Qin et al., 2019)