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Each sensor protein recognizes specific ligands and undergoes conformational changes upon ligand binding to initiate inflammasome assembly

The increased ROS production during ferroptosis can also contribute to tumor cell proliferation

2.5 In vivo therapeutic effects of Ru SA+AC on ACLT-induced rat OA model Given the remarkable enzyme-like properties, mitochondrial protection, and anti-inflammatory effects demonstrated by Ru SA+AC in vitro, its therapeutic potentials for OA were further investigated based on rat models of OA induced by ACLT, followed by intra-articular injection of g-C 3 N 4 and Ru SA+AC nanozymes

Among them, we can highlight obesity, chronic heart failure, Alzheimers disease, cancer, diabetes, and autoimmune diseases