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(1987) indicate that plasma cells may reduce antibody production upon exposure to -AR specific amines, including noradrenaline (71)

Recent studies have shown that extracellular vesicles (EVs), particularly exosomes (30120 nm vesicles derived from multivesicular body-plasma membrane fusion), as critical mediators of intercellular communication [17, 18]

Further research is needed to validate these findings and explore the integration of radiomics with other clinical and laboratory data to enhance predictive accuracy

This suppression results in reduced production of pro-inflammatory cytokines, such as TNF- and IL-6, which are central to the pathogenesis of fibrosis