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doi: 10.1016/j.expneurol.2024.114770, 52 LiaoY.LiuM.WangH.WalshV.LauC

In astrocytes, Mn-induced ER stress activates the PERK/eIF2 pathway and promotes a detrimental A1-reactive phenotype, linking ER stress to astrocyte-driven inflammation and Mn neurotoxicity 178

Scientists use these documented pharmacokinetic characteristics to explore how tissues respond to oxidative stress and mechanical injury at a microscopic level