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Although discovered several decades ago, studies continue to identify pro-inflammatory roles for leptin and anti-inflammatory activities for adiponectin, hormones secreted in large amounts by the adipocyte

PMID: 39499390 Cell Biochem BiophysPotential Action Mechanism of Erianin in Relieving MNNG-triggered Chronic Atrophic Gastritis

For example, IF has been shown in overweight and obese human subjects during Ramadan to modulate expression of SIRT1, SIRT3, and antioxidant genes, though results are mixed and often depend on gene expression rather than direct functional assays [38]