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Conclusion: Systemic inflammation and immunodeficiency are important components of immune dysfunction in patients with cirrhosis

This shift increases metabolic stress and dependence on fatty acids, resulting in excessive oxygen use and metabolic imbalance, with the accumulation of lipid intermediates and ROS

Understanding the molecular dynamics of collagen fiber formation, the mechanotransduction pathways that regulate cellular responses to mechanical stress, and the genetic factors that predispose individuals to weaker ligament structures can inform more effective prevention and rehabilitation strategies

We then performed single or combination treatment using the GLUT1 inhibitor BAY-876 and YBX1 inhibitor SU056