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Die Folge knnen Mdigkeit, Muskelschwche, Konzentrationsschwierigkeiten, ein geschwchtes Immunsystem und Muskelkrmpfe sein

Despite the identification of N-acetyl cysteine, a reactive oxygen species scavenger that is regarded as an effective clinical treatment, therapeutic effectiveness remains limited due to rapid disease progression and diagnosis at a late phase, which leads to the need to explore various therapeutic approaches

Dialysis was set up overnight at 4 C to remove the His-SUMO tag from the complex with TEV protease (250 mM NaCl, 50 mM tris pH 7.5, 10% glycerol, 5 mM magnesium chloride, 1 mM TCEP)